Equipment that measures permeation through membranes

A SES flow type Franz cell is a standard Franz cell with additional porting for circulating receptor medium continuously through the receptor compartment of the cell. As with static Franz cells, flow porting may also be added to the donor compartment if needed. The phrases "flow thru", "flow cell", and "flow type" are used interchangeably and refer to flow only through the receptor compartment, and do not signify anything with respect to the heating jacket. The first five codes for ordering codes flow thru Franz cells are the same as for static cells. A sixth code, FT, is added to the end of the first five codes and the variety of flow porting is followed by donor codes. Receptor volumes for flow type cells are larger than for the static cells of the same orifice diameter because the distance between the top of the heating jacket and the bottom of the joint is greater to accommodate the arms for the flow work.

Flow thru Franz cells are currently available in four different varieties and are shown at the bottom of this page.

The word "orifice" as it refers to a Franz Cell is the area of the top of the receptor chamber that is exposed to the membrane or device through which transport or permeation is being studied. Standard orifice diameters are 5mm, 7mm, 9mm, 11.28mm, 15mm, 20mm and 25mm, other diameters are custom. Corresponding volumes from 5ml to 20ml are standard and are listed below. There are minimum volumes, especially for jacketed cells, please find those in the list below as well. We welcome requests for custom cells! Clamping is achieved through standard o-ring joints, flat ground (ground o-ring) joints and flat flange joints. Please note that for most the most popular Franz Cell models we manufacture our own cell clamps. These clamps are all stainless steel and are much easier to use than clamps from other suppliers.

 

Ordering Information - Part numbers are generally made up of 2-character codes separated by hyphens.

•    1st code is cell type: 4G is for a jacketed cell, 6G is for an unjacketed cell
  
   
•    2nd code is joint type:
     - 00 is an o-ring joint
     - 01 is a flat ground (ground o-ring) joint
     - 02 is a flat flange joint
     - 03 is a spherical joint generally used for corneal work.
  
   
•    3rd code is glass type: 00 is for clear glass, 01 is for amberized glass
  
   
•    4th code is orifice diameter in millimeters, 05 through 25
  
   
•    5th code is receptor volume in ml, 03 through 20
  
   
•    6th code is FT indicating a flow type cell
  
   
•    7th code is 01 through 04 indicating the configuration of the flow ports according to 
     the variety of flow cell desired. The four present varieties are pictured below.
  
   
•    8th code is optional and indicates:
     - VD is for a volatile donor compartment with ground glass joint and Teflon stopper
     - VDFT is for a flow through volatile donor compartment with ground glass joint and Teflon stopper
     - VDOC is for an completely occluded volatile donor compartment
     - VDOF is for flow thru volatile donor compartment without ground glass joint and Teflon stopper
  
   
•    9th code only follows the 8th VD or VDFT codes if a stoppered donor is required:
     - 0725 is for a 7/25 ground glass joint with teflon stopper
     - 1420 is for a 14/20 ground glass joint with teflon stopper

• #4G-01-00-09-05 is for a 9mm jacketed cell with a flat ground (ground o-ring) joint and clear glass with a 5ml receptor volume
• #6G-02-01-05-05 is for a 5mm unjacketed cell with a flat flange joint and amberized glass with a 5ml receptor volume
• #4G-03-00-05-03 is for a 5mm jacketed cell with a spherical joint and clear glass with a 3ml receptor volume.

•    Vertical Stirrer Side View
   
•    Available Joints
   
•    O-Ring Joint Cells
   
•    Flat Ground (Ground O-Ring) Joint Cells
   
•    Flat Flange Joint Cells
   
•    Flat Flange type Franz Cell with flow ports in receptor
   
•    Flat Ground type Franz Cell with Volatile Flow Type Donor Compartment
   

•    V3 3-Station Franz Cell Stirrer
   
•    6-Station Franz Cell Stirrers
   
•    V9-C Compact 9-Station Franz Cell Stirrer
   
•    V9 9-Station Franz Cell Stirrer

These dimensions are for standard Franz cells, the joints variety does not affect the volume. We can modify most any of these parameters within the practical limits of blown glass. Do not hesitate to inquire if your studies need something other than what is listed here. The term "cell" for sales and pricing purposes includes the two glass components, the clamp for the joint, and the stirbar.

 
Standard jacketed cells with clamp and stirbar

•      5mm:5ml volume (4ml minimum) - .20 square cm area
   
•      7mm:5ml volume (4ml minimum) - .38 square cm area
   
•      9mm:5ml volume (7ml minimum) - .64 square cm area
   
•    11.28mm:8ml volume (10ml minimum) - 1.00 square cm area
   
•    15mm:12ml volume (11ml minimum) - 1.77 square cm area
   
•    20mm:15ml volume (16ml minimum) - 3.14 square cm area
   
•    25mm:20ml volume (25ml minimum) - 4.91 square cm area
   

Standard unjacketed cells with clamp and stirbar

•      5mm:5ml volume (1ml minimum) - .20 square cm area
   
•      7mm:5ml volume (1ml minimum) - .38 square cm area
   
•      9mm:5ml volume (1.5ml minimum) - .64 square cm area
   
•    11.28mm:8ml volume (2ml minimum) - 1.00 square cm area
   
•    15mm:12ml volume (5ml minimum) - 1.77 square cm area
   
•    20mm:15ml volume (6ml minimum) - 3.14 square cm area
   
•    25mm:20ml volume (10ml minimum) - 4.91 square cm area
   

Call ++49 6736 1301 for current pricing.

Type 1 flow Franz cells are like static Franz cells in that they have a sampling port as well as the flow ports. These cells may be provided with female luer fittings and luer stoppers on the ends of the flow ports so they can also be sampled through the sampling arm and therefore used as static cells if desired.
 

Type 2 flow Franz cells are just like Type 1 cells except that the manual sampling port is not present.